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Kumada Coupling. The Kumada Coupling was the first Pd or Ni-catalyzed cross coupling reaction, developed in 1972. The coupling of Grignard reagents with alkyl, vinyl or aryl halides under Ni-catalysis
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2019-6-19 · In computing and systems design a loosely coupled system is one in which each of its components has, or makes use of, little or no knowledge of the definitions of other separate
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